It was decades later that the secret behind this spectacular success became known. The East German Sports Federation had, with the help of the Stasi, used Performance Enhancing Drugs or PEDs to ensure that their athletes gained international recognition by winning the Olympic events. This systematic plan had been initiated in 1974 as a means to guarantee international glory through the achievement of gold medals at the prestigious sporting event. Oral- Turinabol , a testosterone derivative was used extensively to improve muscle mass and cut down recovery time. This allowed the German athletes to train harder and longer than other world athletes.
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Anabolic steroids (ABS) boldenone (BL; mg/kg) and stanozolol (ST; mg/kg) were administered . to horses and the plasma samples collected up to 64 days. Anabolic steroids and androgenic steroids (ANS) in plasma were quantified using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The limit of detection of all analytes was 25 pg/mL. The median absorption (t1/2 partial differential) and elimination (t1/2e) half-lives for BL were h and h, respectively, and the area under the plasma concentration-time curve (AUCho) was /mL. The median t1/2e for ST was h and the was /mL. Peak mean (X+/-SD) plasma concentrations (Cmax) for BL and ST were and pg/mL, respectively. Quantifiable concentrations of ABS and ANS were found in % of the 988 plasma samples tested from race tracks. In % of the plasma samples two or more ABS or ANS were quantifiable. Testosterone (TES) concentrations mean (X+/-SE) in racing and nonracing intact males were +/- and +/- pg/mL, respectively. TES was not quantified in nonracing geldings and female horses, but was in racing females and geldings. Plasma concentrations of endogenous 19-nortestosterone (nandrolone; NA) from racing and nonracing males were +/- and +/- pg/mL, respectively.