If my testosterone is low, will I have to take the Testosterone Replacement Therapy forever? Medical studies conclude that it is safe and effective to stay on a TRT program for 20+ years. As long as a patient is monitored every 6-12 months and remains in a normal human testosterone range, there is no need to ‘cycle’ off of testosterone replacement. Should you decide to stop the program, your body will go back to producing those levels it produced prior to therapy (less the natural 1 to 3% testosterone degradation for each of those years and for each year to follow).
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