As noted earlier, Aerocrine also submitted a spreadsheet model to NICE as part of the appraisal process. The model was accompanied by a brief Microsoft PowerPoint slideset although this does not include a description of the intended base-case analysis results and little detail is provided supporting the structure, assumptions or choices regarding evidence used to inform the model parameters. The submitted Aerocrine model adopts a very similar structure and similar assumptions to those of the diagnostic model reported by Price et al. 147 It should be noted that, in the absence of a detailed written description of the Aerocrine submission model, it is difficult to provide a full critique of its methods and results. This task was further hindered as the worksheet tabs and many sets of calculations were structurally hidden within the Microsoft Excel worksheet, making formula auditing problematic.